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Substance P and calcitonin gene related peptide induce TGF-alpha expression in epithelial cells via mast cells and fibroblasts

โœ Scribed by Peter Hoffmann; Karoline Hoeck; Susanne Deters; Ilka Werner-Martini; Wolfgang E. Schmidt


Book ID
116858266
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
343 KB
Volume
161
Category
Article
ISSN
0167-0115

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## Abstract One of the shared physiological roles between TGFโ€ฮฒ and connexin family members is to inhibit epithelial cell cycle progression and consequently, to provide protection against malignant transformation. Herein, we demonstrated that TGFโ€ฮฒ1 induces the expression of connexin43 (Cx43) in no