Subpopulations of CD4−, CD8− thymocytes
✍ Scribed by William C. Gause; John D. Mountz; Alfred D. Steinberg
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 357 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0014-2980
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract In normal mice, more than 10% of thymocytes in the CD4^+^CD8^–^ and CD4^–^CD8^+^ single‐positive (SP) subsets express a medium level of CD3 on the cell surface. However, the fate of CD3^medium^ cells is unclear. The CD3^medium^ SP subpopulations might contain (i) cells in an immature st
A differentiation pathway from CD4+CD8+ cells to CD4+CD8- or CD4-CD8+ cells was investigated in athymic nude mice. Using fluorescence-activated cell sorter, CD4+CD8+ cells were sorted out from AKR thymocytes (H-2k, Thy-1.1) stained with two monoclonal antibodies against CD4 and CD8 (anti-L3T4 and an