## Abstract The majority of patients with chronicโphase (CP) chronic myeloid leukemia (CML) who are treated with BcrโAbl tyrosine kinase inhibitors such as imatinib and dasatinib achieve cytogenetic disease remission (ie, Philadelphia chromosomeโpositive cells undetectable by cytogenetic evaluation
Suboptimal responses in chronic myeloid leukemia : Implications and management strategies
โ Scribed by Elias Jabbour; Giuseppe Saglio; Timothy P. Hughes; Hagop Kantarjian
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 840 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0008-543X
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## Abstract ## BACKGROUND: The European LeukemiaNet recommendations for chronic myeloid leukemia (CML) defined a group of patients with suboptimal response to imatinib. The significance of this response was not well defined. ## METHODS: The significance of having had a suboptimal response during