Submillimeter isotropic resolution carotid wall MRI with swallowing compensation: Imaging results and semiautomated wall morphometry
✍ Scribed by Ioannis Koktzoglou; Debiao Li
- Book ID
- 102905742
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 724 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1053-1807
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Purpose
To assess a swallowing‐compensated, three‐dimensional (3D) diffusion‐prepared segmented steady‐state free precession (3D Nav‐D‐SSFP) technique for carotid wall MRI with 0.6‐mm isotropic spatial resolution, and its utility for semiautomated carotid wall morphometry.
Materials and Methods
The carotid arteries of seven healthy volunteers (N = 14) were imaged with 3D Nav‐D‐SSFP and black‐blood T2‐weighted (T2w) two‐dimensional (2D) fast spin‐echo (FSE). Carotid wall‐lumen contrast‐to‐noise ratio (CNR) was measured with both sequences. Measurement of carotid wall area (WA) and lumen area (LA) made in a semiautomated manner off of the 3D Nav‐D‐SSFP images were compared to those made manually.
Results
Adjusted for voxel volume and number of slices, a near six‐fold improvement in CNR per unit time was achieved with 3D Nav‐D‐SSFP relative to 2D T2w FSE (P < 0.001). Manual and semiautomated measurements of carotid WA and LA on the 3D Nav‐D‐SSFP images were highly correlated (intraclass correlation coefficient (ICC) = 0.961 and 0.996, respectively; P < 0.001).
Conclusion
3D Nav‐D‐SSFP is a time‐efficient, swallowing‐compensated, black‐blood technique that lends itself for semiautomated measurements of carotid WA and LA that are in good agreement with manual measurements. J. Magn. Reson. Imaging 2007. © 2007 Wiley‐Liss, Inc.