Submicroscopic detection of immunoglobulin receptors on lymphocyte surface membranes
β Scribed by K. A. Zufarov; K. R. Tukhtaev; A. M. Mikliev
- Publisher
- Springer US
- Year
- 1982
- Tongue
- English
- Weight
- 721 KB
- Volume
- 93
- Category
- Article
- ISSN
- 0007-4888
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Using [3H]-dopamine (DA) as the ligand of choice, we have shown that rat lymphocytes possess DA binding sites. The binding of r3H]-DA was specific, saturable, and of high affinity. The specific binding in membranes obtained from Con A-activated lymphoblasts was greater than the binding in respective
## Abstract Living lymphocytes of the Elasmobranch fish, __Raja naevus__, have been examined for surface immunoglobulin (Ig) by treatment with a fluorescent antiβIg system. Large numbers of Igβpositive cells (60β80%) were found in peripheral blood, spleen and thymus. Following modulation of the sur