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Subgroup analysis of BL-cell lines with polyclonal bl-specific antibodies

✍ Scribed by Yair Gazitt; Barbro Ehlin-Henriksson; Ana Lerner; George Klein


Publisher
John Wiley and Sons
Year
1984
Tongue
French
Weight
418 KB
Volume
34
Category
Article
ISSN
0020-7136

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✦ Synopsis


A Burkitt's lymphoma (BL)-specific antibody (anti-GP70), previously described, was used to analyse 22 different BL-cell lines. The results indicated specificity of antibodies to lines that contain both surface membrane Ig (SmIg) and cytoplasmic Ig (CyIg). BL-cell lines derived from more immature B cells that do not have SmIg but rather have only CyIg were negative. A comparative study with antibody to common ALL antigen (CALLA) and to another BL-specific antigen (BLA) revealed coexpression of GP70 with those two antigens, but no identity between them.


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