Subclass distribution of human IgG autoantibodies in pemphigus
โ Scribed by Christian C. Jones; Robert G. Hamilton; Robert E. Jordon
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 839 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0271-9142
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Bullous pemphigoid and pemphigus are autoimmune disorders of skin of unknown etiology and are characterized by the presence of immunoreactants in the skin and circulating autoantibodies to skin components. The distribution of IgG subclass antibodies to intercellular substance (ICS) of pemphigus and
## Background: Pemphigus vulgaris (pv) autoantibodies (pv-igg) have been found in 40-70% of sera of first-degree relatives of pemphigus patients. ## Objectives: To determine the possible role of pv-igg subclasses in the pathogenesis of the disease. ## Patients and methods: Study groups comprise