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Subchronic milnacipran treatment increases basal extracellular noradrenaline concentrations in the medial prefrontal cortex of rats

✍ Scribed by Yuji Kitaichi; Takeshi Inoue; Takeshi Izumi; Shin Nakagawa; Akiko Kato; Tsukasa Koyama

Book ID: 113585590
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 129 KB
Volume: 520
Category: Article
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2005.08.004

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## Abstract Substance P receptor antagonists cause antidepressant‐ and anxiolytic‐like effects in rodents that are thought to involve brain monoamines. In the present study, we examined the effects of the NK1 receptor antagonist GR‐205,171 on basal and stress‐induced rise of extracellular noradrena