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Subcellular trafficking of HPMA copolymer–Tat conjugates in human ovarian carcinoma cells

✍ Scribed by Aparna Nori; Keith D. Jensen; Monica Tijerina; Pavla Kopečková; Jindřich Kopeček

Book ID
114162388
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
350 KB
Volume
91
Category
Article
ISSN
0168-3659

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The binding, internalization, subcellular trafficking and in vitro cytotoxicity of N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-anti-cancer drug-OV-TL16 antibody (Ab) conjugates in the ovarian carcinoma OVCAR-3 cell line have been investigated. Adriamycin (ADR) and meso chlorin e6 mono(N-2-ami