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Subcellular trafficking abnormalities of a prion protein with a disrupted disulfide loop

✍ Scribed by Anat Yanai; Zeev Meiner; Inbar Gahali; Ruth Gabizon; Albert Taraboulos


Book ID
117111556
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
314 KB
Volume
460
Category
Article
ISSN
0014-5793

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## Abstract Most of type 2A von Willebrand disease (VWD) mutations are clustered within the A2 domain of VWF, encoded by the 3β€² region of exon 28 of the von Willebrand factor (VWF) gene. A patient with lifelong and severe bleeding diathesis and laboratory data of type 2A VWD is described. The analy