The acquired immunodeficiency syndrome (AIDS) frequently involves the central nervous system (CNS) and manifests as dementia due to encephalitis or diffuse neurodegeneration. Human immunodeficiency virus type 1 (HIV-1) proteins, potentially transported into the CNS by mononuclear inflammatory cells,
Subcellular localization of the interaction between the human immunodeficiency virus transactivator Tat and the nucleosome assembly protein 1
β Scribed by Alex De Marco; Pablo D. Dans; Anna Knezevich; Paolo Maiuri; Sergio Pantano; Alessandro Marcello
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 723 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0939-4451
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## Abstract Human immunodeficiency virus type 1 (HIVβ1)βassociated dementia is observed in 20β30% of patients with acquired immunodeficiency syndrome (AIDS). The Ο΅4 allele of the apolipoprotein E (APOE) gene currently is thought to play a role as a risk factor for the development of HIV dementia. T
In vitro, beta-herpesviruses can stimulate or inhibit HIV replication under particular circumstances. In order to investigate the effects of beta-herpesvirus infection on HIV replication and vice versa at an organ level, we determined the quantitative relationships between cytomegalovirus (CMV), hum