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Subcellular Localization of Accumulated p53 in Ovarian Cancer Cells

✍ Scribed by Ingo B. Runnebaum; Dirk G. Kieback; Volker J. Möbus; Xiao-Wen Tong; Rolf Kreienberg

Book ID
115616842
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
165 KB
Volume
61
Category
Article
ISSN
0090-8258

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Increased accumulation of p53 protein in
Increased accumulation of p53 protein in cisplatin-resistant ovarian cell lines
✍ Robert Brown; Carol Clugston; Angela Edlin; Paul Vasey; Stanley B. Kaye; Philip 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 French ⚖ 942 KB

## Abstract We have examined p53 protein levels in cell lines selected for resistance to the chemotherapeutic drug __cis__‐diamminedichloroplatinum (II), cisplatin. The majority of the independent cisplatin‐resistant clones isolated by a single selection with cisplatin from the ovarian tumour cell