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Subcellular localization and trafficking of polycystins

✍ Scribed by Michael Köttgen; Gerd Walz


Book ID
106109628
Publisher
Springer
Year
2005
Tongue
English
Weight
302 KB
Volume
451
Category
Article
ISSN
0031-6768

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✍ Peters, Dorien J. M.; van de Wal, Annemiek; Spruit, Lia; Saris, Jasper J.; Breun 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 469 KB 👁 1 views

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the formation of fluid-filled cysts in both kidneys, in addition to a variety of extra-renal manifestations. The PKD1 gene product, polycystin-1, encodes a novel protein with a putative role in cell-cell/cell-matrix interaction