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Subcellular distribution and cofactor function of human branched chain α-ketoacid dehydrogenase in normal and mutant cultured skin fibroblasts

✍ Scribed by Dean J. Danner; Louis J. Elsas II


Book ID
115766480
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
1001 KB
Volume
13
Category
Article
ISSN
0006-2944

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We investigated changes in cell growth and branched chain ketoacid dehydrogenase (BCKD) activity by varying the concentrations of branched-chain amino acids (BCAAs) in culture medium of diploid fibroblasts from humans with normal BCKD and with impaired enzyme function. For logarithmic growth the two