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Subacute toluene exposure increases DA dysfunction in the 6-OH dopamine lesioned nigrostriatal dopaminergic system of the rat

✍ Scribed by A. Cintra; B. Andbjer; U.-B. Finnman; M. Hagman; L.F. Agnati; G. Höglund; K. Fuxe


Book ID
116126012
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
639 KB
Volume
217
Category
Article
ISSN
0304-3940

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The in vivo dopamine (DA) receptor binding and behavioural properties of the recently characterised putative preferential DA autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 were studied in rats with a unilateral 6-OH-DA lesion of the substantia nigra. The main findings were a) that (+)-UH 232 and