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Subacute oral toxicity of tri-n-butyl phosphate in the sprague–dawley rat

✍ Scribed by S. Laham; G. Long; B. Broxup

Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
609 KB
Volume
4
Category
Article
ISSN
0260-437X

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✦ Synopsis

Tri-n-butyl phosphate was administered by gavage to male and female Sprague-Dawley rats for 14 consecutive days (low dose: 0.14 ml kg-'; high dose: 0.42 ml k-'). Effects of this chemical were investigated at the end of the feeding period. Histopathological examination of the testes (highdose group) showed the presence of microscopic degenerative changes in the seminiferous tubules. No other abnormal microscopic changes were observed. * 0.01 < p < 0.05; exposed group vs. control group.

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