𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Su2040 Relative Potencies of Bile Acids in Inducing Fibroblast Growth Factor 19 in the Human Ileum

✍ Scribed by Kennie, Sarah; Nolan, Jonathan D.; Zhang, Justine H.; Johnston, Ian M.; Dixon, Peter H.; Williamson, Catherine; Walters, Julian R.

Book ID
122309560
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
60 KB
Volume
144
Category
Article
ISSN
0016-5085

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Bile acids activate fibroblast growth fa
Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7Ξ±-hydroxylase gene expression
✍ Kwang-Hoon Song; Tiangang Li; Erika Owsley; Stephen Strom; John Y. L. Chiang πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 685 KB

Mouse fibroblast growth factor 15 (FGF15) and human ortholog FGF19 have been identified as the bile acid-induced intestinal factors that mediate bile acid feedback inhibition of cholesterol 7␣-hydroxylase gene (C YP7A1) transcription in mouse liver. The mechanism underlying FGF15/FGF19 inhibition of

High expression of the bile salt-homeost
High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis
✍ Frank G. Schaap; Niels A. van der Gaag; Dirk J. Gouma; Peter L. M. Jansen πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 320 KB

Fibroblast growth factor 19 (FGF19) is an endocrine factor produced by the small intestine in response to uptake of luminal bile salts. In the liver, FGF19 binds to FGF receptor-4, resulting in down-regulation of cytochrome P (CYP) 7A1 and reduced bile salt synthesis. Down-regulation of CYP7A1 under