✦ LIBER ✦

SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization

✍ Scribed by Ismail, Ismail Hassan; Mårtensson, Susanne; Moshinsky, Deborah; Rice, Audie; Tang, Cho; Howlett, Anthony; McMahon, Gerald; Hammarsten, Ola

Book ID: 110068383
Publisher: Nature Publishing Group
Year: 2003
Tongue: English
Weight: 323 KB
Volume: 23
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1207303

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Lack of detectable defect in DNA double-

Lack of detectable defect in DNA double-strand break repair and DNA-dependent protein kinase activity in radiosensitive human severe combined immunodeficiency fibroblasts

✍ Nathalie Nicolas; Nicholas J. Finnie; Marina Cavazzana-Calvo; Dora Papadopoulo; 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 503 KB

The initial step of the V(D)J recombination occurs through the generation of a DNA double-strand break (dsb). Defects in the DNA-dependent protein kinase complex (DNA-PK) result in an inability to perform either V(D)J recombination or any dsb repair effectively. The human autosomal T-B-severe combin

Ku70/80 gene expression and DNA-dependen

Ku70/80 gene expression and DNA-dependent protein kinase (DNA-PK) activity do not correlate with double-strand break (dsb) repair capacity and cellular radiosensitivity in normal human fibroblasts

✍ Kasten, U; Plottner, N; Johansen, J; Overgaard, J; Dikomey, E 📂 Article 📅 1999 🏛 Nature Publishing Group 🌐 English ⚖ 184 KB

The use of a double-marker shuttle vecto

The use of a double-marker shuttle vector to study DNA double-strand break repair in wild-type and radiation-sensitive mutants of the yeastSaccharomyces cerevisiae

✍ Bhavanath Jha; Fred Ahne; Friederike Eckardt-Schupp 📂 Article 📅 1993 🏛 Springer-Verlag 🌐 English ⚖ 628 KB

An episomal DNA vector (YpJA18), encoding two selectable recombinant yeast genes (TRP1, URA3), was constructed to assess the fidelity of DNA repair in haploid repair-competent (RAD) wild-type yeast and several radiation-sensitive mutants. Either a DNA double-strand break (DSB) or a double-strand gap