Hepatic steatosis is a common histologic feature in patients with chronic hepatitis C (CHC) but there are no large longitudinal studies describing the progression of steatosis in CHC. We examined changes in steatosis on serial biopsies among CHC patients participating in the Hepatitis C Antiviral Lo
Su1026 Statin Use Reduces Risk of Progression of Liver Fibrosis, Among Patients With Chronic Hepatitis C: Analysis of the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial
โ Scribed by Simon, Tracey G.; King, Lindsay Y.; Zheng, Hui; Chung, Raymond T.
- Book ID
- 123361326
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 374 KB
- Volume
- 146
- Category
- Article
- ISSN
- 0016-5085
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Studies of the prognostic value of Ishak fibrosis stage are lacking. We used multi-year follow-up of the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial to determine whether individual Ishak fibrosis stages predicted clinical outcomes in patients with chronic hepatitis C.
Combination treatment with pegylated-interferon-alpha (PEG IFN-โฃ) and ribavirin, the current recommended therapy for chronic hepatitis C virus (HCV) infection, results in a sustained virological response (SVR) in only about half of patients. Because genes involved in the interferon-alpha pathway may