No-carrier-added DL-alpha-methyl-beta-4-[18F]fluorophenyl-N-methyl-N-propynylethylamin e (DL-4-[18F]fluorodeprenyl) was synthesized via the following 3-step procedure: (1) nucleophilic aromatic substitution by [18F]fluoride on 4-nitrobenzaldehyde to produce 4-[18F]fluorobenzaldehyde (yield 65%); (2)
โฆ LIBER โฆ
Study on the synthesis of 6-alkylaminouridines via the nucleophilic aromatic substitution reaction of 6-cyanouridine derivatives
โ Scribed by Jian-Bang Lin; Jhih-Li He; Yu-Chiao Shih; Tun-Cheng Chien
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- French
- Weight
- 340 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0040-4039
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## Nucleophilic aromatic substitution / Oxidative nucleophilic substitution of hydrogen The reaction of primary amines bearing tertiary alkyl groups substituted to afford N,Nะ-di(tert-alkyl)-4-nitro-2-nitroso-1,3phenylenediamines 8a,b. The addition of oxidizing agents (e.g. R-NH 2 ; R = tBu, 1-ada