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Study on the sorption properties of α1-acid glycoprotein (AGP)-based stationary phase modified by organic solvents

✍ Scribed by Krisztina Gyimesi-Forrás; György Szász; Gábor Báthory; György Mészáros; András Gergely


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
153 KB
Volume
15
Category
Article
ISSN
0899-0042

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✍ Krisztina Gyimesi-Forrás; György Szász; Zsuzsa Budvári-Bárány; András Gergely 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 158 KB

A binding study on ␣ 1 -acid glycoprotein (AGP), a widely used chiral stationary phase in drug analysis, has been performed. Being a selectivity decisive factor in enantiomer separation, the adsorption of the organic modifiers, as the regularly used acetonitrile (AcCN) and also of dioxane, was deter