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Study on the apoptosis of Raji cell line induced by arsenic trioxide and its correlation with Survivin gene

✍ Scribed by Yi Long; Huimin Li; Chen Qing; Hua Liu; Zhang Yanli; Yu Meijia


Publisher
Springer
Year
2008
Tongue
English
Weight
634 KB
Volume
7
Category
Article
ISSN
1610-1979

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The mechanism of the induction of apoptosis by arsenic trioxide (As 2 O 3 ), which was demonstrated recently to be an effective inducer of apoptosis in patients with leukemia, was examined in detail in human leukemia U937 cells. Upon treatment of U937 cells with 50 M of As 2 O 3 , complete inactivat