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Study on Synthesis of Thebaine Derivatives

โœ Scribed by He Liu; Chun-He Liu; Bo Wu; Bo-Hua Zhong; Ze-Hui Gong

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
72 KB
Volume
23
Category
Article
ISSN
0256-7660

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โœฆ Synopsis

Study on Synthesis of Thebaine Derivatives

LIU, He*(ๅˆ˜ๆฒณ) LIU, Chun-He(ๅˆ˜ๆ˜ฅๆฒณ) WU, Bo(ๅดๆณข) ZHONG, Bo-Hua(ไปฒไผฏๅŽ) GONG, Ze-Hui(ๅฎซๆณฝ่พ‰)

๐Ÿ“œ SIMILAR VOLUMES

The synthesis of thebaine-1-3H
The synthesis of thebaine-1-3H
โœ Satish C. Choudhry; Lucia Serico; Joseph Cupano; David H. Malarek; Arnold A. Lie ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 250 KB

A synthesis of thebaine is described where the C-1 position is labelled with tritium to specific activity of 16 Ci/mmole. From codeine (a, 1iodocodeine ( 1 ) was prepared and converted to 1-iodothebaine (T, in 3 steps. The subsequent key reaction was the selective hydrogenolysis of the carbon-iodine