✦ LIBER ✦

Study on slow release anti-cancer drugs prepared by radiation induced polymerization

✍ Scribed by Xie Huaijiang; Song Juzhong; Peng Tao

Book ID: 103990333
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 217 KB
Volume: 42
Category: Article
ISSN: 0969-806X
DOI: 10.1016/0969-806x(93)90405-j

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✦ Synopsis

This paper reports the research results which the anticancer drugs Ara-C with controlled slow release were made by radiation induced polymerization of monomers such as methacrylates at room temperature. Our studies showed that not only hydrophilic synthetic polymers but also hydrophobic polymers such as hydrophobic methacrylateslincluding MMA,EMA,and BMA) could be used to the immobilization.In vitro the rate of drugs release was controlled by the many factors such as the content of drugs~the monomer material.the crosslinking agent.the irradiation dose and the water content,etc.

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