𝔖 Bobbio Scriptorium
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Study on Lewis acid promoted condensation of allylalkoxysilanes with (-)-menthyl glyoxylate

✍ Scribed by Yong-Jun Chen; Liang Huang; Dong Wang; Ji-Sheng Li


Book ID
112060266
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
440 KB
Volume
12
Category
Article
ISSN
0256-7660

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Diastereocontrol via lewis acid-promoted
✍ Kōichi Mikami; Teck-Peng Loh; Takeshi Nakai πŸ“‚ Article πŸ“… 1988 πŸ› Elsevier Science 🌐 French βš– 213 KB

Taking the judicious choice of the Lewis acid employed, the glyoxylate ene reactions are shown to proceed with a high level of either erythro or threo diastereoselection. The utility of the ene methodology is demonstrated through the stereocontrolled synthesis of a 22F&hydroxy-23-carboxylate steroid