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Study on developmental abnormalities in hypospadiac male rats induced by maternal exposure to di-n-butyl phthalate (DBP)

✍ Scribed by JunTao Jiang; Long Ma; Lin Yuan; XinRu Wang; Wei Zhang

Book ID: 108287407
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 655 KB
Volume: 232
Category: Article
ISSN: 0300-483X
DOI: 10.1016/j.tox.2007.01.018

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## Abstract Adult male rats gestationally exposed to di(n‐butyl)phthalate (DBP) have dysgenetic testes characterized by seminiferous epithelial degeneration, clustering of Leydig cells, and decreased spermatogenesis. Cell proliferation and apoptosis are key processes regulating development of the t