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Study of the tolerance and diuretic properties of torasemide following oral or intravenous administration to healthy volunteers

✍ Scribed by R. Lambe; O. Kennedy; M. Kenny; A. Darragh; L. Dodion


Publisher
Springer
Year
1986
Tongue
English
Weight
544 KB
Volume
31
Category
Article
ISSN
0031-6970

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## Abstract The effect on digit‐symbol substitution (DSST) of duration and extent of exposure to midazolam was studied in seven healthy male volunteers. Individual pharmacokinetic and pharmacodynamic parameters were estimated after a 7Β·5 mg intravenous bolus dose of midazolam. Subjects then receive