Study of the susceptibility of anti-tumor drug resistant cells to IL-1 induced LAK cells
โ Scribed by K. Hirata; U. Lee; Y. Sakurai; Y. Sasakura; J. Sindo
- Book ID
- 117612000
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 216 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0901-5027
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The susceptibility of tumor cells from cultures of 8 human colorectal tumor explants to a standard LAK preparation originating from a single healthy donor was assessed in 5 various cytotoxic tests. Target cells were suspended or attached (in three different 51Cr-release 4 hr tests), grown as a confl
Drug resistance has been associated with resistance to NKand LAK-cell-mediated cytotoxicity. We evaluated this issue in human cell lines, using multiple myeloma cells (8226) and 2 multi-drug-resistant (MDR) sublines selected using doxorubicin (8226/Dox40) and mitoxantrone (8226lMR40). In parallel, w