𝔖 Bobbio Scriptorium
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Study of the Mutagenic Activity of Extracts of the Plant Wilbrandia ebracteata

✍ Scribed by Ana Maria Costa Braga Pereira; Mareni Rocha Farias; Vera Maria Ferrão Vargas

Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
431 KB
Volume
10
Category
Article
ISSN
0951-418X

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✦ Synopsis

The present study was carried out to investigate the mutagenic activity of six extracts of the plant W&mndia ebmcteutu (family Cucurbitacea), one of the species found in products commercially sold as 'TaiuiSi'. The method for investigation was the Salmonellalmicrosome assay using strains TA100, TA98 and TA102 In assays carried out in the presence or absence of S9Mix as the activating system. The results indicate the absence of mutagenic activity in flavonoid and cucurbitadn-rich fractions. Signs of an increased mutagenic index were detected in the methanol fractions prepared from dried roots. We observed an increased dose response below a revertant rate, which was twice the spontaneous yield.

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