✦ LIBER ✦
Study of the in vivo fixation of antibodies on tumors provoked in hamsters by injection of SV40-transformed cells (TSV5Cl2)
✍ Scribed by E. Sobczak; Ch. de Vaux Saint Cyr
- Publisher
- John Wiley and Sons
- Year
- 1971
- Tongue
- French
- Weight
- 430 KB
- Volume
- 8
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
✦ Synopsis
Large particle fraction obtained by the technique of
Sjogren and Motet (1969)
can be treated at acid P H , to elute immunoglobulins from hamster tumors induced by injection of SV-40 transformed fibroblasts (TSV,CI,). The eluate contains IgGz 7S, as well as two fragments having molecular weights of about 67,000; one of these, Fc, migrates in the /l region, and the other, F(ab), migrates in the slow y region. This eluate, tested on TSV,Cl in culture, contains some cytotoxic antibodies and antibodies against T antigen and cytoplasmic antigen.