Study of the Effect of Mobile Phase Additives on Retention in Reversed Phase HPLC Using Linear Solvation Energy Relationships

Supramolecular effects in chiral discrim

Supramolecular effects in chiral discrimination of clenbuterol enantiomers in RP-HPLC system with helically self-assembled mobile-phase additive. Retention studies and molecular modeling approach

✍ Grzegorz Bazylak; Hassan Y. Aboul-Enein 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 240 KB 👁 2 views

The standard RP-HPLC mode with a conventional octadecylsilicapacked column and the chiral chelate (-)(M)(,⌳)-[4,4Ј-((1S)-methyl-(2R)propylethanediyldiimino)bis(pent-3-en-2-onato)]nickel(II), with a flexible, helically selfassembled structure, as the chiral selector in a mobile phase of acetonitrile-