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Study of the Cis to Trans Isomerization of 1-Phenyl-2,3-disubstituted Tetrahydro-β-carbolines at C(1). Evidence for the Carbocation-Mediated Mechanism

✍ Scribed by Kumpaty, Hephzibah J.; Van Linn, Michael L.; Kabir, M. Shahjahan; Försterling, F. Holger; Deschamps, Jeffrey R.; Cook, James M.


Book ID
126261875
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
276 KB
Volume
74
Category
Article
ISSN
0022-3263

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Enantiospecific Formation of trans-1,3-Disubstituted Tetrahydro-βcarbolines by the Pictet-Spengler Reaction and Conversion of cis Diastereomers into Their trans Counterparts by Scission of the C-1/N-2 Bond. -The factors which effect the stereoselective formation of trans-products in the Pictet-Spen