Study of quaternary ‘onium’ salts grafted on polymers: antibacterial activity of quaternary phosphonium salts grafted on ‘gel-type’ styrene–divinylbenzene copolymers

✍ Scribed by Adriana Popa; C.M. Davidescu; R. Trif; Gh. Ilia; Smaranda Iliescu; Gh. Dehelean

• Publisher: Elsevier Science
• Year: 2003
• Tongue: English
• Weight: 281 KB
• Volume: 55
• Category: Article
• ISSN: 1381-5148
• DOI: 10.1016/s1381-5148(02)00224-9

✦ Synopsis

This paper deals with the synthesis and characterization of compounds with antibacterial activity: quaternary phosphonium salts grafted on macromolecular supports by polymer-analogous reactions. The products were proved to have antibacterial activity against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. A great advantage was that the active species grafted on insoluble carriers could be used in repeated cycles, only needing sterilization prior to use.