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Study of ischemic myocardial buffering capacity in perfused rat heart through rapidly interleaved 1H and 31P MRS measurements

✍ Scribed by Adam E. Schussheim; George K. Radda


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
498 KB
Volume
30
Category
Article
ISSN
0740-3194

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✦ Synopsis


Abstract

We present a method for the direct correlation of quantitative changes in lactate concentration and intracellular pH during global ischemia in the perfused rat heart using rapidly interleaved ^31^P MRS and water‐suppressed ^1^H MRS acquisitions. The ischemic myocardial buffering capacity was determined and found to be consistent with previous experimentation.