Study of inorganic arsenic methylation by rat liver in vitro: relevance for the interpretation of observations in man
β Scribed by J. P. Buchet; R. Lauwerys
- Book ID
- 104731467
- Publisher
- Springer-Verlag
- Year
- 1985
- Tongue
- English
- Weight
- 514 KB
- Volume
- 57
- Category
- Article
- ISSN
- 0340-5761
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## Abstract The toxicity of inorganic trivalent arsenic for living organisms is reduced by __in vivo__ methylation of the element. In man, this biotransformation leads to the synthesis of monomethylarsonic (MMA) and dimethylarsinic (DMA) acids, which are efficiently eliminated in urine along with t
## Abstract The contents of the rat small intestine or caecum reduced sodium [^74^As] arsenate to arsenite over a period of 2β3 days. In the presence of caecal, but not small intestine, contents, small amounts of methyl arsonic acid and dimethylarsinic acid were formed. Stomach contents reduced ars