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Study of in vitro and in vivo effects of the piperidine nitroxide Tempol—a potential new therapeutic agent for gliomas

✍ Scribed by M.B Gariboldi; R Ravizza; C Petterino; M Castagnaro; G Finocchiaro; E Monti

Book ID: 117659232
Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 395 KB
Volume: 39
Category: Article
ISSN: 0959-8049
DOI: 10.1016/s0959-8049(02)00742-6

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## Abstract Osteolysis, that is, progressive periprosthetic bone loss, is responsible for approximately 70% of aseptic loosening and implant failure. Usually, it is due to a granulomatous reaction wear‐induced, leading to macrophage and osteoclast‐mediated bone resorption. At present, there is no e