Study of enzymatic G6P synthesis using polymer-bound ATP in membrane reactors
✍ Scribed by Wael Abdelmoez; Kosaku Ishimi; Haruo Ishikawa
- Publisher
- American Institute of Chemical Engineers
- Year
- 2006
- Tongue
- English
- Weight
- 169 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0001-1541
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The performance of membrane reactors, in which the enzymatic synthesis of glucose 6‐phosphate from glucose and polymer‐bound cofactor ATP with simultaneous regeneration of polymer‐bound ATP from polymer‐bound ADP and acetyl phosphate are performed, was analyzed theoretically. Simplified and realistic models for two different membrane reactors, a plug‐flow–type membrane reactor (PFMR) in a diffusion mode and a continuous stirred tank reactor–type membrane reactor (CSTMR) in a filtration mode, were presented and compared theoretically. The results showed that the reactor performance mainly depends on the operating conditions and that, in most cases, the PFMR in a diffusion mode was found to be superior to the CSTR in a filtration mode. This study provides useful information for selecting and optimizing of the reactor for enzymatic reactions requiring cofactors. © 2005 American Institute of Chemical Engineers AIChE J, 2006