✦ LIBER ✦

Study of Correlations in DNA Sequences

✍ Scribed by V.R. Chechetkin; A.Y. Turygin

Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 604 KB
Volume: 178
Category: Article
ISSN: 0022-5193
DOI: 10.1006/jtbi.1996.0017

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✦ Synopsis

We present a method for unified statistical analysis of short and long range correlations between various nucleotides in genomic DNA strands. The approach is based on the mutual study of Fourier structure factor spectra and pair correlation functions. The analysis of cross correlations in the different ranges of structural spectra permits identification of the main sources of correlations, namely, the coherent point mutations, coincident periodicities or large scale density variations. The technique for assessment of structural coupling between various genes in the genome is also described.

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