Study of baicalin scavenging hydroxyethyl peroxyl radicals by radiolysis of aerated ethanol-baicalin system
✍ Scribed by Cai Zhongli; He Yongke; Wu Jilan
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 194 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0969-806X
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✦ Synopsis
The reaction of baicalin (fl-D-glucopyranosiduronic acid, 5,6-dihydroxy-oxo-2-phenyl-4H-1benzopyran-7-yl) scavenging hydroxyethyl peroxyl radicals (RO~) was studied with the aid of radiolysis of aerated ethanol. Two main stable products were separated by reverse HPLC and their possible molecular structures were derived from their UV, IR and FAB-MS spectra. The dependence of G(H202), G(CH3CHO ) and G(-baicalin) on the concentration of baicalin showed that one baicalin molecule could inhibit the formation of one H202 molecule and two CH3CHO molecules. A possible reaction mechanism between baicalin and RO i radical was suggested.