Development of stable liquid formulation
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Robert K. Evans; Denise K. Nawrocki; Lynne A. Isopi; Donna M. Williams; Danilo R
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Article
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2004
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John Wiley and Sons
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English
โ 252 KB
We have evaluated the stability profiles of adenovirus type-5 (Ad5)-based vaccine formulations to identify liquid formulations that are stable during long-term storage at 48C. By identifying the major physiochemical inactivation pathway(s) during storage, formulations of Ad5 were designed with speci