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Studies with enaminones: Synthesis and chemical reactivity of 2-(4-dimethylamino-2-oxobut-3-enyl)-isoindole-1,3-dione and of 4-(4-dimethylamino-2-oxobut-3-enyloxy)-2H-phthalazin-1-one

✍ Scribed by Saleh Al-Mousawi; Elizabeth John; Najat Al-Kandery

Publisher: Journal of Heterocyclic Chemistry
Year: 2004
Tongue: English
Weight: 194 KB
Volume: 41
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570410312

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✦ Synopsis

Abstract

The title compounds were synthesized via condensing acetonylphthalimide and 4‐acetonyloxyphthalazine‐1‐one with dimethylformamide dimethylacetal (DMFDMA). The reaction of these enaminones with electrophiles and nucleophiles is reported as a route to polyfunctional heteroaromatics.

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