Studies towards the biomimetic synthesis of bisesquiterpene lactones

✍ Scribed by Sharanjeet K Bagal; Robert M Adlington; Rodolfo Marquez; Andrew R Cowley; Jack E Baldwin

• Book ID: 104253846
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 179 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)01172-9

✦ Synopsis

A possible biomimetic connection between atractylolide, hydroxyatractylolide and biatractylolide and biepiasterolide has been demonstrated by efficiently generating the biatractylolide and biepiasterolide core structures from atractylolide and hydroxyatractylolide model butenolides via a radicaloid intermediate in a single step in good yield.