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Studies Towards Simalikalactone D (Ia) and Quassimarin (Ib): Construction of an Advanced Pentacyclic Intermediate (II).

✍ Scribed by Tony K. M. Shing; Xue Y. Zhu; Yeung Y. Yeung


Publisher
John Wiley and Sons
Year
2004
Weight
76 KB
Volume
35
Category
Article
ISSN
0931-7597

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Studies towards Simalikalactone D and Qu
✍ Tony K. M. Shing; Xue Y. Zhu; Yeung Y. Yeung πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 341 KB

## Abstract An advanced pentacyclic intermediate, amenable to further elaboration into the target molecules simalikalactone D and quassimarin, has been synthesized from (__S__)‐(+)‐carvone in 21 steps and with an overall yield of 12 %. The synthesis is efficient, stereocontrolled, enantiospecific,