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Studies on vitamin D and related compounds X. Preparation and properties of cis-isotachysterol2

✍ Scribed by A. Verloop; G. J. B. Corts; E. Havinga

Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
516 KB
Volume
79
Category
Article
ISSN
0165-0513

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✦ Synopsis

Abstract

The photochemical conversion of isotachysterol~2~ (in ether) has been studied; the effects of wave‐length and time of irradiation on the composition of the irradiation mixture are discussed. On chromatography of the crude irradiation product a compound was obtained in a pure, non‐crystalline form. The compound did not show antirachitic activity. The ultra‐violet and infra‐red absorption spectra, the iodine‐catalysed quantitative conversion to isotachysterol~2~, the behaviour on heating in solution and the very low reactivity towards maleic anhydride led to the conclusion that the compound is the Δ6,7‐cis isomer of isotachysterol~2~, i.e. 9,10‐secoergosta‐5(10),6‐cis, 8(14), 22‐tetraen‐3β‐ol.

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