Studies on tumor promoters. 10. Synthesi
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Paul A. Wender; Frank E. McDonald
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Article
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1990
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Elsevier Science
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French
β 295 KB
A novel synthetic route to the ABC ring system of the daphnanes and tiglianes based on intramolecular enyne carbocyclixation is described that provides access to a new family of diterpene tumor promoter analogs. Phorbol lZmyristate 13-acetate has long been of interest in cancer research as one of th