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Studies on the toxicology of hexachlorobenzene

✍ Scribed by G. Koss; S. Seubert; A. Seubert; W. Koransky; H. Ippen

Book ID: 104716589
Publisher: Springer-Verlag
Year: 1978
Tongue: English
Weight: 587 KB
Volume: 40
Category: Article
ISSN: 0340-5761
DOI: 10.1007/bf00310334

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After administration of hexachlorobenzene rats excrete sulphur-containing conjugates from which pentachlorothiophenol can be split off. In the present study we describe the identification of pentachlorothiophenol and pentachlorothioanisol in the livers of animals treated with hexachlorobenzene. In o

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Female rats were dosed intraperitoneally with 14C-hexaxhlorobenzene. The drug was administered on 2 or 3 occasions. The total doses amounted to 260 and 390 mg/kg 14C-hexachlorobenzene, respectively. Urine and feces from the animals were collected over a period of 4 weeks after the first injection. B

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In female rats dosed orally with 14C-hexachlorobenzene the extent of intestinal absorption of carbon-14 has been found to be dependent on the form of application. When the substance was given as a solution in oil about 80% of the dose administered was absorbed, but when given as an aqueous suspensio

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