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Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell

✍ Scribed by Rick Greupink; Hester I. Bakker; Catharina Reker-Smit; Anne-miek van Loenen-Weemaes; Robbert-Jan Kok; Dirk K.F. Meijer; Leonie Beljaars; Klaas Poelstra

Book ID: 116650766
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 265 KB
Volume: 43
Category: Article
ISSN: 0168-8278
DOI: 10.1016/j.jhep.2005.04.014

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## Abstract Hepatic stellate cells (HSCs) are the major site of retinol (ROH) metabolism and storage. GRX is a permanent murine myofibroblastic cell line, derived from HSCs, which can be induced to display the fat‐storing phenotype by treatment with retinoids. Little is known about hepatic or serum