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Studies on the release of exogenous and endogenous GABA and glutamate from rat brain synaptosomes

โœ Scribed by Giulio Levi; Miriam Banay-Schwartz; Maurizio Raiteri


Publisher
Springer
Year
1981
Tongue
English
Weight
599 KB
Volume
6
Category
Article
ISSN
0364-3190

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Valproate (VPA) and vigabatrin (gamma-vinyl GABA, GVG) are two novel antiepileptic drugs with a presumed GABAergic mechanism of action. However, for VPA, this aspect has been extensively debated. The aim of the present study was to investigate whether treatment of cultured neurons with clinically re