𝔖 Bobbio Scriptorium
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Studies on the regulation of carbohydrate synthesis during growth and differentiation ofPhysarum polycephalum

✍ Scribed by A. Hüttermann; M. Gebauer; G. Brand; I. Wessel

Publisher
Springer
Year
1974
Tongue
English
Weight
601 KB
Volume
98
Category
Article
ISSN
0302-8933

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✦ Synopsis

During the starvation-induced spherulation of the true slime mold Physarum polycephalum, a metabolic shift occurs from glycogen synthesis during growth to slime (polygalactose) secretion during this differentiation. The synthesis rate of glycogen during growth is 3.5 spec. mU, of slime during spherulation 2.1 spec. mU. The specific activity of UDPGpyrophosphorylase (EC 2.7.7.9) increases during the first nine h of starvation by about 40~ and then decreases. After 24 h of starvation only 300/0 of the specific activity present during growth is left. During differentiation induced by 0.5 mannitol its specific activity decreases continuously, without an initial increase, to about 25~ of the initial value. The specific activity of UDPGpyropbosphorylase is not influenced by the addition of cycloheximide or actinomycin-C during the differentiation.

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