Studies on the Preparation of 3,4-Disubstituted 2-Methoxypyridines. -The synthesis of 2-methoxy-4-methylpyridine-3-carbonitrile (III) starting from known nitrile (I) and its conversion into pyridylacetic acid ester (XVII) via alkylation of the C-4 methyl group is described. -(PELISSON, MARCELO
✦ LIBER ✦
Studies on the preparation of 3,4-disubstituted 2-methoxypyridines
✍ Scribed by Marcelo M. M. Pelisson; Gil Valdo José Da Silva; Derrick L. J. Clive; Don M. Coltart; Fraser A. Hof
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 1999
- Tongue
- English
- Weight
- 504 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0022-152X
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✦ Synopsis
Abstract
The synthesis of 2‐methoxy‐4‐methylpyridine‐3‐carbonitrile (3) and its conversion, by way of alkylation of the C(4) methyl group, into the pyrodyl acetic acid ester 6 is described.
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